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The Ultimate Guide to Protein Supplements

Caught like a deer in the headlights when trying to choose the right protein powder? Here's an all-inclusive guide to help you pick the right supplement for you.
The Ultimate Guide to Protein Supplements
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Flip through any exercise magazine and, judging by all the attention protein supplements get, it appears protein and fitness somehow go hand-in-hand The effects of six weeks of supplementation with multi-ingredient performance supplements and resistance training on anabolic hormones, body composition, strength, and power in resistance-trained men. Ormsbee MJ, Mandler WK, Thomas DD, et al. Journal of the International Society of Sports Nutrition, 2012 Nov 15;9(1):49. Effects of a high protein diet on body weight and comorbidities associated with obesity. Baker, Clifton P. IDI Heart and Diabetes Institute, University of South Australia, Adelaide, Australia. The British Journal of Nutrition, 2012 Aug;108 Suppl 2:S122-9.. And it is true: Protein can help promote a healthy weight and can help muscles recover after a good workout. But what exactly is protein, and when it comes to supplements, which type of protein is best? Read on to learn about the different sources of protein powder and which ones stand apart from the rest.

Protein 101—The Need-to-Know

Protein is a macronutrient found in many foods such as meats, dairy products, nuts, and beans, to name a few. It’s comprised of amino acids, the building blocks of lean body tissue that promote healthy skin, hair, bones, fingernails, as well as (drum roll, please) muscles Dietary protein - its role in satiety, energetics, weight loss and health. Westerterp-Plantenga MS, Lemmens SG, Westerterp KR. Human Biology, Nutrim, MUMC, Maastricht University, Maastricht, Netherlands. British Journal of Nutrition. 2012 Aug;108 Suppl 2:S105-12.. While many experts suggest getting the bulk of our protein from whole food sources, protein supplements can make it easier to get those aminos on-the-go. But not all protein supplements are created equal Effect of intake of different dietary protein sources on plasma amino Acid profiles at rest and after exercise. Burke LM, Winter JA, Cameron-Smith D, et al. Australian Institute of Sport, Belconnen, Australia Capital Territory, Australia. International Journal of Sport Nutrition and Exercise Metabolism, 2012 Dec;22(6):452-62.. Before dissecting the pros and cons of different protein sources it’s important to understand two ways protein supplements are often classified:

  • Protein Concentrate vs. Isolate: Protein is derived from various food sources and is "concentrated" by removing the non-protein parts. The result: a powder that’s 70-85 percent pure protein (with the remain 15-30 percent consisting mostly of carbohydrates and fat). Taking the concentration process a step further, "isolation" removes a much higher percentage of non-protein content. The additional processing yields a premium protein that is up to 95 percent pure.
  • Complete vs. Incomplete Protein: Amino acids that cannot be produced by the body are known as essential amino acids. "Complete proteins" contain all 10 essential amino acids, whereas "incomplete proteins" contain some, but not all, of the essential amino acids.

OK, now we are ready to dive into the fun stuff. Here is a detailed look at the most common protein powder supplements on the market, and what their pros and cons mean for you. 

What's Up With Supps?—Protein Comparison

Whey Protein

The most popular protein supplement on the market today, whey is a by-product in the process of turning milk into cheese (seriously, who knew it happened like this?). 

Pros: Whey protein has been shown to promote lean muscle growth and fat loss, as well as support cardiovascular health and a healthy metabolism Impact of milk consumption and resistance training on body composition of female athletes. Josse AR, Phillips SM. Department of Kinesiology, Faculty of Science, McMaster University, Hamilton, Ontario, Canada. Medicine and Sport Science, 2012;59:94-103. Epub 2012 Oct 15. The effects of whey protein on cardiometabolic risk factors. Pal S, Radavelli-Bagatini S. School of Public Health, Curtin Health Innovation Research Institute, Curtin University of Technology, Perth, Western Australia, Australia. Obesity reviews : An Official Journal of the International Association for the Study of Obesity, 2012 Nov 20.. Whey is also quickly absorbed by the body, making it useful for post-workout recovery. Bonus: This inexpensive source of complete protein comes in a variety of flavors ranging from tried-and-true vanilla to decadent chocolate-mint ice cream. (Sorry, we couldn't find a cheddar cheese flavor for those looking to stay true to whey's roots!) 

Cons: The sugar found in milk (aka lactose) is a common allergen that can make whey indigestible for some. And while those tasty flavors make whey a yummy choice, they often (depending on the brand) come with a host of less-than-desirable artificial sweeteners and chemicals.

Casein Protein

Got milk? Well here's another protein powder that comes straight from the udder (figuratively speaking of course!). Casein is produced using a separation process applied to liquid milk that can concentrate or isolate the milk protein from the carbs and fats. 

Pros: Casein protein powder offers similar benefits to whey protein, but with a different release process. Because casein digests over a long period of time, research has found it’s an optimal protein choice before bed. (Yum—bedtime protein shake!)

Cons: Casein is a by-product of milk, making it allergenic to some, much like whey. Also, it’s not ideal as a post-workout supplement because it’s absorbed so slowly. After exercise the body craves nutrients to replenish and rebuild—which is best left to whey or a combination of the two. Casein also more expensive than whey, and often contains many artificial ingredients to help make it more palatable.

Egg Protein

Egg protein comes from, well, eggs! It is a complete protein made by separating out the yolks and dehydrating the egg whites. 

Pros: Aside from just protein, egg protein powders are rich in vitamins and minerals that can contribute to a healthy diet. 

Cons: Allergies to eggs are common, similar to milk allergies, especially in children and young adults Food allergy in childhood. Szépfalusi Z. Univ.-Prof. für Kinder- und Jugendheilkunde, Medizinische Universität Wien, Wien, Österreich, zsolt. Wiener Medizinische Wochenschrift, 2012 Nov 22.. Egg protein is also one of the most expensive protein supplements available, which is likely why Rocky Balboa did it this way. 

Soy Protein

Soy beans are one of the few plant protein sources that offer all of the essential amino acids. The protein is concentrated or isolated after the soy beans have been hulled and dried into soy flour (which also makes for delicious pancakes!).

Pros: Protein from the soy bean may help improve the body's immune function and promote bone health Soy foods: are they useful for optimal bone health? Lanou AJ. Therapeutic Advances in Musculoskeletal Disease, 2011 Dec;3(6):293-300.. Soy may also help prevent cardiovascular disease and reduce the risk of certain cancers Effect of soybean protein on novel cardiovascular disease risk factors: a randomized controlled trial. Rebholz CM, Reynolds K, Wofford MR, et al. Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA. European Journal of Clinical Nutrition, 2012 Nov 28.. 

Cons: In recent years, soy has come under heavy scrutiny because it is often genetically modified to produce greater crop yields. Some research has also singled out soy due to its effects on hormone levels. Many foods are already full of soy due to its extremely low-cost protein. This has led some to question whether adding even more dietary soy (via protein supplements) is a wise choice.

Rice Protein

News flash: There is protein in rice! Although often thought of as a carbohydrate only, brown rice is becoming a standard source for vegetarian protein powder. 

Pros: Protein aside, brown rice protein is considered a good source of complex carbohydrates, vitamin B, and fiber. It’s also hypoallergenic, meaning it’s easily digestible and therefore almost entirely used by the body, not relieved as waste.

Cons: Unlike soy, rice protein is a plant-based option that’s deficient in some amino acids and therefore should not comprise the main source of dietary protein.

Hemp Protein

Hemp protein is derived from the seeds of the cannabis plant that’s gained popularity in recent years. (And yes, we are talking strictly about hemp as a food source here!)

Pros: Often referred to as a "superfood" due to its mix of essential fatty acids, hemp has been shown to improve metabolism, brain function, and circulation, and can help treat a host of medical conditions. Hemp also includes all 21 amino acids (making it a complete protein). The vegan-friendly supplement is also extremely hypoallergenic, high in fiber (read: excellent for digestion and filling), which makes it an excellent weight-loss food.

Cons: Since hemp is only harvested in mass quantities in select countries due to its association with cannabis, it is often the most expensive protein powder available.

Pea Protein

Thought you’ve seen them all? Pea protein comes from the yellow split pea,  making it a popular choice for vegetarians and vegans alike.

Pros: As with most plant-based proteins, pea protein is hypoallergenic. It boasts a 98 percent digestion rate, meaning the body is able to process the vast majority of each serving. It is another highly satiating protein, which may help promote weight loss  The effects of high protein diets on thermogenesis, satiety and weight loss: a critical review. Halton TL, Hu FB. Dept. of Nutrition, Harvard School of Public Health, Boston, MA. Journal of the American College of Nutrition, 2004 Oct;23(5):373-85.. And with few additives or artificial ingredients, this one appeals to those looking for protein sources closest to the whole-food source. Don't like peas? Don't worry, the protein version doesn’t taste like mush!

Cons: Isolated pea protein is often considered complete because it can contain the spectrum of essential amino acids. Even still, it remains deficient in certain amino acids and should not be used as a primary source of dietary protein. 

Weight Gainer

Looking to bulk up? Weight gainer combines protein, often whey, with a mix of high-carbohydrate ingredients that makes it much more calorie-dense than typical protein powders. It is often used by bodybuilders who are looking to pack on the pounds, or by serious athletes who have difficulty consuming enough calories to offset the large amount they burn through intense training Nutrition and sports performance. Brotherhood JR. Auckland, NZ. Sports Medicine. 1984 Sep-Oct;1(5):350-89..

Pros: Jam-packed with calories, weight gainers allow people to consume more calories than they could through food alone. They also help keep the grocery bill in check by delivering calories at a (slightly more) economical price.

Cons: Unsurprisingly, weight gainers often contain many additives, artificial sweeteners, and fillers so that they can pack the calorie and protein punch their users are looking for. It’s also worth mentioning that the huge calorie count in these products doesn’t necessarily translate to more muscle. In fact, all those extra calories will be stored as fat if not needed for recovery after intense exercise.

To the Protein Aisle!—The Takeaway

When it comes to protein powders there really is something for everyone. Just keep in mind that when it comes to buying protein, as in life, "You get what you pay for." Low-cost proteins often use inexpensive protein blends that may not be very digestible by the body. It is also worth noting that the amount of protein required by the body depends on a person’s activity level, physical size, and gender. Testing various sources and quantities of protein can help determine a mix that works best. And just because it’s easy to chug a shake after a workout doesn't mean protein powders should replace whole foods entirely. Protein powders are supplements, best used to supplement a healthy diet of nutritious whole foods.

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