Alcohol. It can be just the buzz we need on a night out or a cozy evening in. But how does alcohol get you drunk?

For better or worse, people drink booze for many reasons. Maybe they want to calm their nerves after a fraught day at the office. Perhaps they need to inflate their self-esteem when approaching someone they fancy.

They might instead be looking to drown their sorrows upon realizing the world is nothing more than a grain of sand on a vast cosmic beach. Cheers!

But why do our bodies and brains react in the way they do when alcohol enters our systems? We sip from the cup of truth, with a chaser of science.

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Ethanol is the key ingredient in alcohol and the active component that gets you drunk. According to a 1997 study with rats, ethanol forms when yeast ferments the sugars in plants.

The sugar in barley makes beer, the sugar in grapes makes wine, and the sugar in potatoes makes vodka (go on, admit you didn’t know that last one).

It moves from the brewery to the bottle/can/tap to your mouth. From there, it causes effects through your body, gets you buzzed, and often kicks you right into a hangover the next day.

(You don’t have to get hangovers — here’s how to prevent them.)

Alcohol is a depressant. But it also has stimulating effects that start to take effect pretty much from the moment a drink touches your lips.

But you don’t just digest alcohol. It also flows through your bloodstream, making pit-stops at every part of your body. And it triggers unique effects in each one.

Let’s follow the alcohol in its journey as it rapidly slides down your system like a biological Splash Mountain.

Your mouth

Here’s where the ride begins.

As soon as alcohol passes your lips, the liquid combines with your saliva. Then, it finds its way into your bloodstream through tiny blood vessels in your mouth and on your tongue.

Your gut and stomach

According to the Health Promotion Agency, your bloodstream absorbs 20 percent of alcohol via your stomach. The remaining 80 percent comes from your small intestine.

Drinking small amounts of alcohol can stimulate your appetite because it increases the flow of stomach juices. The more food you eat, the longer the alcohol will stick around. This allows your stomach to absorb the alcohol and break it down before it reaches your small intestine and bloodstream.

Without grub in your gut, the concentration of alcohol in your blood quickly spikes, according to a small 1997 study. This is why it’s best not to drink on an empty stomach. Ethanol can also make your poops runny — here’s how.

Some people use alcohol in recipes — which might not suit nondrinkers. Learn how to replace booze in your brunch here.

Your blood

Now we’re into the bloodstream. (To continue the theme park ride metaphor: the rapids.)

Alcohol causes several sensations in your body. It enters your blood (eww) and widens your blood vessels. According to American Addiction Centers, this could result in:

  • skin flushes (and the trademark red face or discoloration)
  • a rapid change in body temperature (you might get warmer or cooler)
  • a drop in blood pressure

This occurs until your liver can break down the alcohol.

Your brain and nervous system

Meanwhile, what’s happening upstairs? Alcohol’s powerful effect on your brain means it can dull the parts that control how your body works.

Say goodbye to that self-control you once had. Alcohol affects your mood, actions and — most importantly — your decision-making, according to a small 2012 study.

At the beginning you may feel happy and uninhibited. This is down to the booze releasing the greatest hits of chemical brothers dopamine and serotonin — two hormones that make you feel good.

However, these physical effects change as you drink more. You’ll start to experience:

  • slurred words
  • blurred vision
  • loss of coordination
  • low mood or aggression

Yes, watching someone ‘piss-pronounce their worms’ and fall over leaning on the bar can be hilarious. But on the inside, alcohol is depressing their central nervous system and interfering with the brain’s communication pathways, according to a 2013 research review.

Excessive drinking can cause changes in your cognition and memory (wait, you did what last night?). And, it’ll take some time before you change back into your Clark Kent “Soberman” alter ego.

Your kidneys

Down in your kidneys, the alcohol is increasing your urine production. This is because of the antidiuretic hormone (ADH). This is a hormone that causes your kidneys to release more water.

You’ll be peeing like a powerful horse by the end of the night.

But lots of peeing and not drinking enough nonalcoholic fluids will make you thirsty and dehydrated — and even drunker. That’s why you’re supposed to drink a glass of water between each round.

Your lungs

The alcohol you drink also subjects your airways to high levels of alcoholic vapor, according to a research review. This vapor diffuses from your blood into your lungs.

This is why breathalyzer tests can tell whether you should be getting behind the wheel.

Heavy drinking can damage your airways and increase your risk of developing a lung infection, according to another research review

Your liver

Now we come on to the granddaddy: your liver. Through various pathways, the liver ultimately converts alcohol into water and carbon dioxide to eliminate it from your body, according to the National Institute on Alcohol Abuse and Alcoholism.

One 2005 research review showed that your liver eliminates more than 90 percent of alcohol in your blood. But your liver can only process one unit of alcohol per hour. So, your liver’s at the most risk from heavy drinking. Working it too hard isn’t a good idea.

Alcohol f*cks with your liver because this amazing organ gets its blood directly from your intestines — where most alcohol absorption happens.

Your liver helps make you less drunk by reducing the alcohol in your bloodstream. It certainly affects how long alcohol stays in your system.

Here are some other factors that impact on how drunk you feel when you’re sippin’:

  • Weight. According to a small 2010 study, alcohol can mess with your metabolic function depending on your body weight. Higher body weight = more body water content = fewer effects from alcohol. Folks with a lower body mass index may feel the effects of alcohol more intensely — and faster.
  • Sex. Males and females may have different tolerances. A research review showed that females have a lower water content throughout their bodies, and they are a bit smaller in size. So, they may experience the effects from alcohol more often.
  • Age. Aging also interferes with your body’s tolerance to alcohol. The National Institute on Alcohol Abuse and Alcoholism recommends that adults more than 65 years old stick to one drink a day or less.
  • Medication. According to a 1999 research review and a study, any medications you take can alter the effects of alcohol and vice versa. Be very careful when mixing that cocktail. Adderall, for example, is a complete no-go for mixing with alcohol.
  • Type of alcohol. Different drinks have varying amounts of alcohol content. A pint of beer will pack less of a wallop than a pint of whiskey (and please, please, please never drink a pint of whiskey in one go). As they say, it’s not the size that counts. It’s how you use it.
  • Your personality. These factors affect what types of emotions you experience. Your personality can have a huge impact. Who you are and who you’re drinking with (and whether you’re even drinking with others) can have a huge impact on how being drunk makes you feel.

In one small 2006 study, moderate consumption of alcohol reduced circulation of the stress hormone cortisol and increased levels of “feel-good” hormones such as endorphins and oxytocin. These supply those happy, pleasant, and carefree feelings.

But the key emphasis here is “moderate consumption.” And, it may not be the alcohol that’s making you feel good. Drinking is a fun, social activity — you’re hanging out with friends, and you might be celebrating a special occasion.

As 2020 showed us by taking parties away — being social is special. And it’s still special when you’re not drunk. So, try to disassociate that buzz from genuine happiness. A drink or two is a great social lubricant. Vomiting into a gutter at 4:00 a.m. is not a joyful activity.

The short-term behavioral effects of alcohol share the same traits as the short-term effects of other drugs. The greater the dose, the greater the effects — and the higher the peak from which you nosedive.

Those buzzy, first-drunk feelings are always only temporary. You can plummet from cloud nine to ground zero in a heartbeat.

According to the National Institute on Alcohol Abuse and Alcoholism, another slippery slope with links to alcohol misuse is binge drinking. This can increase the risk of blackouts, overdose, and the likelihood of potentially fatal consequences.

When it comes to any drug, remember these three words that could help save your life: Everything 👏🏽 in 👏🏽 moderation 👏🏽... Alcohol can have legit benefits too.

When you get wavy, alcohol enters your blood through your mouth, gut, and stomach, and even your lungs.

Your brain releases feel-good hormones and your kidneys generate a lot of pee. Your liver responds by breaking the alcohol down into water and carbon dioxide.

However, those feel-good vibes can quickly turn to confusion, slurred speech, and risky decisions. And regularly getting on them can lead to long-term and potentially fatal complications in your liver, heart, and stomach.

It’s fine to get merry every so often. Just keep a handle on it. And those who want to get cruuuuuuuuunk should also learn a few tips on relieving hangovers.